Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (8): 2664-2681.DOI: 10.6023/cjoc202305011 Previous Articles     Next Articles


刘颖杰a, 石岗庆a, 仇格b, 张鑫c, 宋冬雪a, 陈宁a, 于淼a, 许颖a,*()   

  1. a 哈尔滨商业大学药学院 哈尔滨 150076
    b 烟台大学化学化工学院 烟台 264005
    c 哈尔滨医科大学附属第一医院 哈尔滨 150001
  • 收稿日期:2023-05-10 修回日期:2023-06-25 发布日期:2023-07-27
  • 基金资助:
    黑龙江省自然科学基金(LH2020H068); 黑龙江省教育厅创新人才(UNPYSCT-2018139); 高校学科协同创新成果建设培育(LJGXCG2022-086)

Progress of α-Position Functionalization of Ethers under Photo/Electrocatalysis

Yingjie Liua, Gangqing Shia, Ge Choub, Xin Zhangc, Dongxue Songa, Ning Chena, Miao Yua, Ying Xua()   

  1. a School of Pharmacy, Harbin University of Commerce, Harbin 150076
    b School of Chemistry and Chemical Engineering, Yantai University, Yantai 264005
    c The First Affiliated Hospital of Harbin Medical University, Harbin 150001
  • Received:2023-05-10 Revised:2023-06-25 Published:2023-07-27
  • Contact: *E-mail:
  • Supported by:
    The Natural Science Foundation of Heilongjiang Province(LH2020H068); The Innovative Talent Project of Ministry of Education of Heilongjiang Province(UNPYSCT-2018139); The Construction and Cultivation of Collaborative Innovation Achievements of Disciplines in Colleges and Universities(LJGXCG2022-086)

Ethers are widely used in organic chemistry, materials science, biomedicine and other fields due to their excellent physicochemical properties. Among them, tetrahydrofuran/tetrahydrothiophene and their derivatives are the core backbones for building biologically active molecules and complex natural products. In recent years, photo/electrocatalysis has gradually become an important tool for chemists to synthesize novel compounds due to its compliance with the requirements of green chemistry and the unique pathway that mostly involves radical intermediates. The functionalization of α-positions of ethers using photo/electrocatalysis is a green and efficient synthetic strategy. Therefore, the research progress of photo/electro- catalytic functionalization of ether compounds at the α-position is reviewed with ether/sulfide as examples, and a detailed description of some of the mechanisms is provided.

Key words: ethers, photocatalysis, electrocatalysis, photoelectric co-catalysis, functionalization