Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (08): 881-892. Previous Articles     Next Articles




  1. (1南京工业大学制药与生命科学学院 南京210009)
    (2新疆大学化学与化工学院 乌鲁木齐830046)
  • 收稿日期:2004-06-25 修回日期:2004-12-03 发布日期:2005-07-30
  • 通讯作者: 李振江

Asymmetric Synthesis of Tailor-made α-Amino Acids by ChiralAuxiliaries: Glycine Equivalent Approach

LI Zhen-Jiang*,WAN Hong-Gui,WEI Ping,SHI Yu-Hu
OUYANG Ping-Kai   

  1. (1 College of Life Science and Pharmaceutical Engineering, Nanjing University of Tech-nology, Nanjing 210009)
    (2 College of Chemistry and Chemical Engineering, Xinji-ang University, Urumqi 830008)
  • Received:2004-06-25 Revised:2004-12-03 Published:2005-07-30
  • Contact: LI Zhen-Jiang

Tailor-made α-amino acids have played an important role in current life science research and biomedical development. Among the methodologies of α-amino acid asymmetric synthesis, chiral auxiliary strategy received most intensive and extensive investigations. Recent development in this strategy was outlined. Detailed critical review on the glycine equivalent approach in the last ten years was given.

Key words: asymmetric synthesis, chiral auxiliary, glycine equivalent, α-amino acid