Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (03): 298-312. Previous Articles     Next Articles

Review

埃博霉素的合成

刘贤贤a,b,覃雯b,郑炎松*,a   

  1. (a华中科技大学化学系 武汉 430074)
    (b桂林高等师范专科学校化学系 桂林 541001)
  • 收稿日期:2005-11-01 修回日期:2006-03-08 发布日期:2007-02-13
  • 通讯作者: 郑炎松

Total Syntheses of Epothiolones

LIU Xian-Xiana,b,QIN Wenb,ZHENG Yan-Song*,a   

  1. (aDepartment of Chemistry, Huazhong University of Science and Technology, Wuhan 430074)
    (bDepartment of Chemistry, Guilin Normal College, Guilin 541001)
  • Received:2005-11-01 Revised:2006-03-08 Published:2007-02-13
  • Contact: ZHENG Yan-Song

Epothilones are novel macrolactones with excellent taxol-like antitumor activity. The main total syntheses of naturally occurring epothilones and their derivatives are reviewed.

Key words: total synthesis, antitumor medicine, epothilone