Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (07): 866-869. Previous Articles     Next Articles

Original Articles

一个简捷、高效合成松叶蜂性信息素的方法

王子坤,田伟生*,潘鑫复   

  1. (a兰州大学化学化工学院 功能有机分子化学国家重点实验室 兰州 730000)
    (b中国科学院上海有机化学研究所 上海 200032)
  • 收稿日期:2007-01-12 修回日期:1900-01-01 发布日期:2007-06-30
  • 通讯作者: 田伟生*

A Concise Synthesis of the Sex Pheromones of Pine Sawflies

WANG Zi-Kun,TIAN Wei-Sheng*,PAN Xin-Fu   

  1. (a State Key Laboratory of Applied Organic Chemistry, Department of Chemistry, Lanzhou University, Lanzhou 730000)
    (b Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2007-01-12 Revised:1900-01-01 Published:2007-06-30
  • Contact: TIAN Wei-Sheng*

Starting from methyl (R)-5-bromo-4-methylpentanoate (4) obtained from the waste in the degradation of steroid sapogenin, (2S,3S,7S)-3,7-dimethylpentadecan-2-yl acetate (2) and propionate (3) were synthesized via the coupling reaction of 4 with heptyl Grignard in 52% and 49% overall yields respectively.

Key words: methyl (R)-5-bromo-4-methylpentanoate, coupling reaction, sex pheromone of Pine sawfly