Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (8): 1895-1906.DOI: 10.6023/cjoc201512049 Previous Articles     Next Articles



扈晓艳a,b, 胡方芝a,b, 张敏敏a,b, 廖益均a,b, 徐小英a, 袁伟成a, 张晓梅a   

  1. a 中国科学院成都有机化学研究所 成都 610041;
    b 中国科学院大学 北京 100049
  • 收稿日期:2015-12-30 修回日期:2016-04-02 发布日期:2016-04-07
  • 通讯作者: 张晓梅
  • 基金资助:

    国家自然科学基金(No. 21172217)资助项目.

Enantioselective Hydrosilylation of N-Aryl Diaryl Ketimines

Hu Xiaoyana,b, Hu Fangzhia,b, Zhang Minmina,b, Liao Yijuna,b, Xu Xiaoyinga, Yuan Weichenga, Zhang Xiaomeia   

  1. a Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041;
    b University of Chinese Academy of Sciences, Beijing, 100049
  • Received:2015-12-30 Revised:2016-04-02 Published:2016-04-07
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21172217).

Lewis base catalyzed enantioselective hydrosilylation of non-ortho-substituted N-aryl diaryl ketimines was realized. In the presence of 20 mol% of the optimal catalyst, the reactions provided a series of (diarylmethyl)amines with high yields (up to 97%) in moderate to good enantioselectivities (up to 89% ee). The absolute configuration of one product was determined by X-ray crystallographic analysis.

Key words: diarylmethylamines, diaryl ketimines, chiral Lewis base, hydrosilylation