化学学报 ›› 2000, Vol. 58 ›› Issue (10): 1301-1306. 上一篇    下一篇

研究论文

镝促进下醛、酮与炔丙基溴及苯基炔丙基溴的高 选择性反应

李志铭;贾瑜;周景尧   

  1. 复旦大学化学系.上海(200433)
  • 发布日期:2000-10-15

Highly selective reaction of propargyl bromide with carbonyl compounds promoted by metal dysprosium

Li Zhiming;Jia Yu;Zhou Jingyao   

  1. Fudan Univ, Dept Chem.Shanghai(200433)
  • Published:2000-10-15

在金属镝的促进下,醛、酮可与炔丙基溴反应,高选择性高产率地得到相应的高炔丙醇,没有发现连二烯醇的存在。当用苯基炔丙基溴代替炔丙基溴与醛、酮反应时,主要得到了相应的连二烯醇,而没有发现高炔丙醇的存在,由此提出了六元环过渡态的反应机理。

关键词: 镝, 醛, 酮, 炔丙基溴, 苯基炔丙基溴

Promoted by metal dysprosium, aldehydes and ketones could react smoothly with propargyl bromide to afford the corresponding homopropargylic alcohols in good to excellent yields, and no allenic alcohols were found. However, carbonyl compounds only afford the corresponding allenic alcohols when propargyl bromide was replaced by 1-phenyl-3-bromopropargyl bromide, and no homopargylic alcohols were formed.

Key words: DYSPROSIUM, ALDEHYDES, KETONE

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