化学学报 ›› 1992, Vol. 50 ›› Issue (5): 504-507. 上一篇    下一篇

研究论文

合成二苄基二硒醚的新方法

王瑾;周洵钧;范伟强;杜少斌   

  1. 杭州大学化学系;浙江大学化学系
  • 发布日期:1992-05-15

A novel method for the synthesis of dibenzyldiselenide

WANG JIN;ZHOU XUNJUN;FAN WEIQIANG;DU SHAOBIN   

  • Published:1992-05-15

苯骈三氮唑和胺(伯、仲胺: 芳胺、杂环胺或杂环芳胺)、苯甲醛发生Mannich反应, 生成N-取代-1-苯骈三氮唑基苄胺, 它与硒氢化钠反应生成二苄基二硒醚, 反应条件温和, 产率高, 胺和苯骈三氮唑均可回收再利用。

关键词: 胺, 苯甲醛, 曼尼希反应, 苄基二硒醚, 苯并三氮唑, 硒氢化钠

Mannich reaction of benzotriazole with PhCHO and R1R2NH (R1 = Ph, substituted Ph, pyridyl; R2 = H, Me; R1R2N = piperidino, morpholino) gave 51-99% benzotriazoles I, which were treated with NaHSe to give >90% dibenzyl diselenide.

Key words: AMINES, BENZALDEHYDE, MANNICH REACTION

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