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化学学报
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化学学报 ›› 2001, Vol. 59 ›› Issue (10): 1702-1706. 上一篇    下一篇

研究论文

两价钯催化下烯醇钯中间体和亲电试剂的反应研究

张庆海;陆熙炎   

  1. 中国科学院上海有机化学研究所.上海(200032);实验室
  • 发布日期:2001-10-15

Reactions of palladium enolate intermediate with electrophiles under divalent palladium catalysis

Zhang Qinghai;Lu Xiyan   

  1. Shanghai Inst Organ Chem., CAS.Shanghai(200032)
  • Published:2001-10-15

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529

被引次数

2

根据在两价钯催化的亲核试剂－炔烃－α,β-不饱和羰基化合物的串联加成反应中所假设的烯醇钯中间体的机理，研究了炔酸烯丙酯化合物1和亲电试剂在两价钯催化下的反应。使用乙酰氮作为亲电试剂得到了β－乙酰氧基烯基－γ－丁丙酯3，这一结果为烯醇钯中间体的机理提供了一个实验证据。

关键词: 钯, 催化, 烯醇, 亲电试剂, 乙酰氯, 乙酰氧基丁内酯

According to the mechanism involving pallium enolate intermediate in divalent palladium catalyzed nucleophile-alkyne- α,β-unsaturated carbonly tandem additions, the reactions of the enyne ester 1 with electrophiles under the catalysis of divalent palladium were examined. Employing acetyl chloride as the electrophile afforded the β-acetoxyvinyl-γ-butyrolactone 3 as the product, which provided an experimental evidence to the mechanism involving the palladium enolate intermediate.

Key words: PALLADIUM, CATALYSIS, ENOLS, ACETYL CHLORIDE

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