An antibodymembrane was prepared using cyanogem bromide to immobilized horse antibody against human IFN on celluler membrane .after incubated at 37°C for one hour in sample solution, the antibody membrane was put on the and of an iodide selective electrode to form an indicated electrode.another iodide electrode fitted with a celluer membrane immobilized urane worked as a reference electrode the electrode response was measured in the buffer solution 0.1 mmol.dm^-3 KI+4.4 mmol.dm^-3 H2O2+0.1mol.dm^-3 phosphate PH5.0.the results indiucated that the potential response is non-liear.the effect of incubation time antibody activety and the electrolyte concentration on the response potential has been studied. a linearing method of electrode response has been give.

Key words: REACTION MECHANISM, CELLULOSE ACETATE, ION SELECTIVE ELECTRODE, GENE, INTERFERON, IODIDE ION, IMMUNE RESPONSE, ELECTRODE REACTION