A methylated β-cyclodextrin polysiloxane was synthesized and a new immobilization method was described. The values of k, α and Rs of an immobilized chiral capillary were almost the same before and after washing with methanol and dichloromethane. The degree of crosslinking was higher than 90%. The maximum permissible temperature was even up to 260℃. After having been exposed to air for two years, column efficiency and enantioselectivity (Rs) were lost ca. 25% and 10% respectively. Racemic halohydrocarbons and alcohols enantiomers can be directly separated. An application of enantiomeric Enantiomeric separation of α -phenylenthanol and fenoprofen was achieved.

Key words: POLYSILOXANE P, METHYLATION, CYCLODEXTRIN, CAPILLARY CHROMATOGRAPHY, GAS CHROMATOGRAPHY, ELECTROPHORESIS, STATIONARY PHASE, ENANTIOMORPH, BONDED, CROSSLINKING