有机化学 ›› 2015, Vol. 35 ›› Issue (8): 1598-1614.DOI: 10.6023/cjoc201504024 上一篇    下一篇

综述与进展

稀土金属胺化物催化C—N键的形成反应

肖洋, 王千宇, 赵蓓, 姚英明   

  1. 苏州大学材料与化学化工学部 江苏省有机合成重点实验室 苏州 215123
  • 收稿日期:2015-04-18 修回日期:2015-05-25 发布日期:2015-05-29
  • 通讯作者: 赵蓓, 姚英明 E-mail:zhaobei@suda.edu.cn;yaoym@suda.edu.cn
  • 基金资助:

    国家自然科学基金(Nos. 21172165, 21132002, 21372172)、江苏省教育厅优势学科和青蓝工程资助项目.

C—N Bond Formation Reaction Catalyzed by Organo-Rare-Earth Metal Amides

Xiao Yang, Wang Qianyu, Zhao Bei, Yao Yingming   

  1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123
  • Received:2015-04-18 Revised:2015-05-25 Published:2015-05-29
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21172165, 21132002, 21372172), the Priority Academic Program Development of Jiangsu Higher Education Institutions, and the Qing Lan Project.

综述了近年来稀土金属胺化物在催化C—N键形成反应中的应用, 包括催化氢胺化(环化)反应、胺与碳二亚胺的胍化反应、醛和胺的酰胺化反应、胺与腈的成脒反应等, 并探讨了上述反应的反应机理.

关键词: 稀土金属, 胺化物, 氢胺化反应, 胍化反应, 酰胺化反应, 脒的合成

The recent progress on the C—N bond formation reaction catalyzed by organo-rare-earth metal amides includes hydroamination/cyclization, guanidination of carbodiimines and amines, amidation of aldehydes and amines, amidination of amines and nitriles. The mechanisms of these transformations are also described.

Key words: rare-earth metal, amides, hydroamination, guanidination, amidation, amidination