有机化学 ›› 2018, Vol. 38 ›› Issue (4): 752-759.DOI: 10.6023/cjoc201710001 上一篇    下一篇

综述与进展

四丁基碘化铵/过氧化叔丁醇促进C—N键构筑的研究进展

黄依铃, 包雯慧, 朱文明, 魏文廷   

  1. 宁波大学材料科学与化学工程学院 宁波 315211
  • 收稿日期:2017-10-06 修回日期:2017-11-16 发布日期:2017-12-05
  • 通讯作者: 魏文廷 E-mail:weiwenting@nbu.edu.cn
  • 基金资助:

    浙江省自然科学基金(No.LQ18B020002)、宁波大学王宽诚幸福基金资助项目.

Recent Advances in Tetrabutylammonium Iodide/t-BuOOH Promoted C—N Bond Formation

Huang Yiling, Bao Wenhui, Zhu Wenming, Wei Wenting   

  1. School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211
  • Received:2017-10-06 Revised:2017-11-16 Published:2017-12-05
  • Contact: 10.6023/cjoc201710001 E-mail:weiwenting@nbu.edu.cn
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No. LQ18B020002) and the K. C. Wong Magna Fund in Ningbo University.

C-N键构筑是有机合成的基础,对于药物分子、天然产物地合成和多功能材料地开发等具有重要作用,因此受到了广泛关注.近年来,利用四丁基碘化铵/过氧化叔丁醇的无过渡金属催化体系来构筑C-N键取得了诸多进展.该策略反应条件相对温和,反应选择性好,为C-N键构筑提供了一条经济、高效的途径.根据氮源类型的不同,对近年来四丁基碘化铵/过氧化叔丁醇促进的C-N键构筑的研究进展展开论述.

关键词: 四丁基碘化铵, 过氧化叔丁醇, C-N键

The construction of C-N bond is the foundation of organic synthesis, which plays a significant role in the synthesis of drug molecules, natural products and functional materials. Accordingly, it has been received much attention. Recently, the remarkable progress has been made in construction of C-N bond by using n-Bu4NI/t-BuOOH under transition-metal-free condition. Due to the relatively mild reaction condition and excellent selectivity, it provides an economy and efficient approach to construct C-N bond. In this review, the recent advances in this area are summarized on the basis of different nitrogen sources.

Key words: tetrabutylammonium iodide, tert-butyl hydroperoxide, C-N bond