关键词: 芳香族胺, 磺酰胺 P, 方酸, 异方酰胺, 合成, 环丁烯 P, 酮 P, 苯胺 P, 氨基化物, 苯甲酸 P

Fourteen new asymmetric substituted isosqurarylium amides were successfully obtained by the reaction of 3-[ortho-(or para-) carboxy anilino]-4-hydroxy-3-cyclo- butenedione with some sulfanilamides. The common marked characteristic of the structure of these compounds 3a～3f and 4a～4f is that the structure units with medicinal effective sulfanilamide and ortho- (or para-) benzaminic acid existed in the same molecule through the bridging of the tetracarbon ring of squaric acid.

Key words: AROMATIC AMINES, SQUARIC ACID, SULFAMIDE P, BENZAMINE P, KETONE P, CYCLOBUTENE P, BENZENECARBOXYLIC ACID P, AMIDE, SYNTHESIS