SIOC English
有机化学
高级检索

有机化学 ›› 2004, Vol. 24 ›› Issue (4): 444-446. 上一篇    下一篇

研究简报

氮硫杂冠醚及其衍生物的合成

周双生*,a, 程旺兴a, 张国升a, 谢复新b, 倪诗圣b,c   

  1. a安徽中医学院药学系省重点建设示范中心实验室 合肥 230038
    b安徽大学化学系 合肥 230039
    c南京大学配位化学国家重点实验室 南京 210093
  • 收稿日期:2003-05-19 修回日期:2003-07-28 接受日期:2003-10-20 发布日期:2022-09-19
  • 基金资助:
    国家自然科学基金(No. 29871001)和安徽省重点建设示范中心实验室资助项目

Synthesis of Azathiacrown Ether and Its Derivatives

ZHOU, Shuang-Sheng*,a, CHENG, Wang-Xinga, ZHANG, Guo-Shenga, XIE, Fu-Xinb, NI, Shi-Shengb,c   

  1. aProvincial Key Laboratory, Department of Pharmacy, Anhui College of Traditional Chinese Medicine, Hefei 230038
    bDepartment of Chemistry, Anhui University, Hefei 230039
    cState Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing210093
  • Received:2003-05-19 Revised:2003-07-28 Accepted:2003-10-20 Published:2022-09-19
  • Contact: *E-mail: Lch@ahtcm.edu.cn

PDF

86

以噻吩、水杨醛、二胺、溴乙酸、烯丙基氯和丙烯腈为原料合成了4,5:14,15-二苯-3,16-二氧-21-硫-7,12-二氮双环[16.2.1]二十一环-1(20),18-二烯(简称氮硫杂冠醚)及其5种衍生物,经元素分析,IR, 1H NMR和MS谱表征了这些化合物的结构.

关键词: 氮硫杂冠醚, 衍生物, 合成, 表征

A new azathiacrown ether 4,5:14,15-dibenzo-3,16-dioxo-21-thio-7,12-diazabicyclo[16.2.1]heneicosa-1(20),18-diene (2) and itsfive derivatives have been synthesized by using thiophene, salicylaldehyde, diamine, bromoacetic acid, acrylonitrile and allyl chloride as starting materials.The structures of these compounds were characterized by elemental analysis, IR,1H NMR and MS spectra.

Key words: azathiacrown ether, derivative, synthesis, characterization