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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (04): 449-453. 上一篇    下一篇

综述与进展

N-(4-芳基-噻唑-2-基)--(1H-苯并三唑-1-基)苯乙酮腙类衍生物的合成

孙亚栋1，刘方明*,1,2，解正峰1，陈家胜1   

  1. (1 新疆大学化学与化工学院 乌鲁木齐 830046)
    (2 杭州师范学院化学系 杭州 310012)
  • 收稿日期:2004-05-17 修回日期:2004-11-02 发布日期:2005-03-30
  • 通讯作者: 刘方明

Synthesis of New N-(4-Aryl-thiazol-2-yl)-ω-(1H-benzo[d]-1,2,3-triazol-1-yl)acetophenone Hydrazones

SUN Ya-Dong1,LIU Fang-Ming*,1,2,XIE Zheng-Feng1,CHEN Jia-Sheng1   

  1. (1 College of Chemistry and Chemical Engineering, Xinjiang University, Ulumqi 830046)
    (2 Department of Chemistry, Hangzhou teaching College, Hangzhou 310012)
  • Received:2004-05-17 Revised:2004-11-02 Published:2005-03-30
  • Contact: LIU Fang-Ming

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以苯并三唑为原料与-溴代芳基乙酮缩合得-(1H-苯并三唑-1-基)芳基乙酮, 再与硫代氨基脲缩合得到新的缩氨基硫脲. 然后分别与5种ω-溴代芳基乙酮环化得到一系列新的含苯并三唑和噻唑环的苯乙酮腙类Schiff碱. 其结构经IR, 1H NMR, 13C NMR和MS及元素分析确证.

关键词: 苯乙酮腙, Schiff碱, 噻唑, 苯并三唑

Three new substituted acetophenone thiosemicarbazones have been synthesized by condensation reaction of acetophenones with thiosemicarbazide, which reacted with -bromoacetophenone in EtOH under refluxing to give a series of acetophenone hydrazone derivatives. Their structure were characterized by ele-mental analysis, IR , 1H NMR, 13C NMR and MS spectra.

Key words: Schiff base, benzotriazol, acetophenone hydrazone, thiazol