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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (05): 702-706. 上一篇    下一篇

研究简报

2-[5-(3,4,5-三甲氧基苯基)-1,3,4-噻二唑-2-基硫代]-1-(2,3,4-三甲氧基)苯乙酮肟醚合成与抗烟草花叶病毒活性研究

薛伟1,2，宋宝安*,1,2，汪华2，何伟2， 杨松1,2
金林红1,2，胡德禹1,2，刘刚1,2，卢平1,2   

  1. (1贵州大学教育部绿色农药和农业生物工程重点实验室 贵阳 550025)
    (2贵州大学精细化工研究开发中心 贵阳 550025)
  • 收稿日期:2005-08-02 修回日期:2005-11-08 发布日期:2006-04-28
  • 通讯作者: 宋宝安

Synthesis and Anti-TMV Activity of 2-[5-(3,4,5-trimethoxyphenyl)- 1,3,4-thiadiazole-2-ylthiomethyl]-1-(2,3,4-trimethoxy)phenylKetoxime Ether Derivativies

XUE Wei1,2,SONG Bao-An*,1,2,WANG Hua2,HE Wei2,YANG Song1,2
JIN Lin-Hong1,2,HU De-Yu1,2,LIU Gang1,2,LU Ping

  1. (1 Key Laboratory of Green Pesticide and Agriculture Bioengineering of Ministry of Education,
    Guizhou University, Guiyang 550025)
    (2 Research and De-velopment Center for Fine Chemicals, Guizhou University, Guiyang 550025)
  • Received:2005-08-02 Revised:2005-11-08 Published:2006-04-28
  • Contact: SONG Bao-An

PDF

1065

被引次数

55

合成了4个2-[5-(3,4,5-三甲氧基苯基)-1,3,4-噻二唑-2-基硫代]-1-(2,3,4-三甲氧)苯乙酮肟醚新化合物, 并经过元素分析、红外光谱、核磁共振氢谱对其结构进行了表征. 初步生物活性测试表明, 化合物具有一定抗烟草花叶病毒活性.

关键词: 1,3,4-噻二唑, 2,3,4-三甲氧基苯乙酮肟, 合成, 硫醚

Four new 2-[5-(3,4,5-trimethoxyphenyl)- 1,3,4-thiadiazole-2-ylthiomethyl]-1-(2,3,4-trimethoxy)phenyl ketoxime ether derivativies were synthesized and characterized by elemental analysis, IR and 1H NMR spectra. The bioassay of some compounds showed that they had moderate anti-TMV activity.

Key words: 2',3',4'-trimethoxyacetophenoxime, thioether, synthesis, 1,3,4-thiadiazole