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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (07): 912-921. 上一篇    下一篇

综述与进展

手性识别及氨基酸类手性固定相的研究进展

王晓东，姚金水*，魏明星，武光，罗存   

  1. (山东轻工业学院材料科学与工程学院 济南 250100)
  • 收稿日期:2005-06-14 修回日期:2005-12-06 发布日期:2006-07-01
  • 通讯作者: 姚金水

Enantioselection and Development in Chiral Stationary PhaseBased on Amino Acid

WANG Xiao-Dong,YAO Jin-Shui*,WEI Ming-Xing,WU Guang,LUO Cun   

  1. (College of Material Science and Engineering, Shandong Institute of Light Industry, Jinan, 250100)
  • Received:2005-06-14 Revised:2005-12-06 Published:2006-07-01
  • Contact: YAO Jin-Shui

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被引次数

42 | 6

近年来, 手性识别更加凸现出极其重要的现实意义, 而作为分离手性分子应用的手性固定相自然引起了大家的关注．立足于国内外手性固定相的研究成果, 介绍了手性固定相及其分类, 并重点综述了基于氨基酸的手性固定相的发展及其制备方法. 同时, 简要介绍了作为手性固定相对不同异构体的识别机理.

关键词: 手性源, 制备, 氨基酸, 手性识别

In recent years, the enantioselective recognition has more and more important realistic meaning, and naturally the chiral stationary phase as separating chiral molecule has aroused the attention from all analytical chemists. This paper introduces chiral stationary phase and classification, and the development of chiral stationary phase based on amino acid and method of preparation. Meanwhile, the chiral recognition mechanism of the isomers is introduced briefly.

Key words: chiral source, preparation, enantioselective recognition, amino acid