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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (05): 640-642. 上一篇    下一篇

研究简报

离子液体中NaHSO4催化芳香醛与1,3-环己二酮的缩合反应

马晶军，李敬慈，唐然肖，周欣，吴秋华
王春*，张明明，李庆   

  1. (河北农业大学理学院 保定 071001)
  • 收稿日期:2006-04-26 修回日期:2006-09-23 发布日期:2007-05-10
  • 通讯作者: 王春

Condensation of Aromatic Aldehydes with 1,3-Cyclohexanedione Catalyzed by NaHSO4 in Ionic Liquids

MA Jing-Jun, LI Jing-Ci, TANG Ran-Xiao, ZHOU Xin, WU Qiu-Hua
WANG Chun*, ZHANG Ming-Ming, LI Qing   

  1. (College of Sciences, Agricultural University of Hebei, Baoding 071001)
  • Received:2006-04-26 Revised:2006-09-23 Published:2007-05-10
  • Contact: WANG Chun

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以NaHSO4为催化剂, 在离子液体1-丁基-3-甲基咪唑四氟硼酸盐([bmim]BF4)介质中, 由芳香醛与1,3-环己二酮衍生物制备了9-芳基-2,3,4,5,6,7-六氢-2H-氧杂蒽-1,8-二酮衍生物. 在沸水浴中反应1～2 h, 产率达81.2%～93.0%. 该方法反应时间短, 产率高, 催化剂价廉易得, 而且对环境友好.

关键词: 9-芳基-2,3,4,5,6,7-六氢-2H-氧杂蒽-1,8-二酮, 硫酸氢钠, 离子液体

A series of 9-aryl-2,3,4,5,6,7-hexahydro-2H-xanthene-1,8-dione derivatives were synthesized from aromatic aldehydes and 1,3-cyclohexanedione derivatives catalyzed by NaHSO4 in ionic liquids, 1-n-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4). The reactions were carried out in boiling water bath for 1～2 h, and the yield ranged from 1.2% to 93.0%. The catalyst employed is not expensive and the ionic liquid can be reusable. The proposed method is fast, efficient and environmentally friendly.

Key words: 9-aryl-2,3,4,5,6,7-hexahydro-2H-xanthene-1,8-dione, NaHSO4, ionic liquid