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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (01): 155-159. 上一篇    下一篇

研究简报

烷基取代三唑硫酮席夫碱的合成和生物活性研究

孙晓红*,a，陶燕a，刘源发b，贾婴琦b，陈邦b，杨建武a   

  1. (a西北大学化工学院化学研究所 西安 710069)
    (b西北大学化学系 西安 710069)
  • 收稿日期:2007-01-21 修回日期:1900-01-01 发布日期:2008-01-23
  • 通讯作者: 孙晓红

Synthesis and Biological Activities of N-(5-Alkyl-2,4-dihydro-3-thioxo-1,2,4-triazol-4-yl) Schiff Bases

SUN Xiao-Hong*,a, TAO Yana, LIU Yuan-Fab, JIA Ying-Qib
CHEN Bangb, YANG Jian-Wua   

  1. (a College of Chemical Engineering, Chemical Research Institute, Northwest Univer-sity, Xi'an 710069)
    (b Department of Chemistry, Northwest University, Xi'an 710069)
  • Received:2007-01-21 Revised:1900-01-01 Published:2008-01-23
  • Contact: SUN Xiao-Hong

PDF

1038

被引次数

44

用5-烷基-4-氨基-2,4-二氢-1,2,4-三唑-3-硫酮与取代芳醛在酸催化下反应合成了7个席夫碱, 化合物结构用1H NMR, IR和元素分析进行了表征, 对植物病原菌的生物活性测试表明它们具有较好的生物活性.

关键词: 三唑硫酮, 2,4-二氢-1,2,4-三唑-3-硫酮, 生物活性, 合成

Seven Schiff bases have been prepared by an acid catalyzed condensation of 5-alkyl-4-amino- 2,4-dihydro-1,2,4-triazole-3-thione with substituted aromatic aldehydes, the structures of which have been confirmed by 1H NMR, IR spectra and elemental analysis. Their biological activities to several vegetable pathogens have been tested, showing that they exhibited good fungicidal activities.

Key words: 2,4-dihydro-1,2,4-triazole-3-thione, synthesis, Schiff base, biological activity