有机化学 ›› 2008, Vol. 28 ›› Issue (07): 1238-1242. 上一篇    下一篇

研究简报

蒙脱土K10-ZnCl2催化下研磨法合成二吲哚甲烷衍生物

李记太* ; 蔺志平   

  1. (河北大学化学与环境科学学院 河北省分析科学技术重点实验室 保定 071002)
  • 收稿日期:2007-11-18 修回日期:2007-12-17 发布日期:2008-07-28
  • 通讯作者: 李记太

Synthesis of Bis(indol-3-yl)methanes Catalyzed by Montmorillonite K10-ZnCl2 by Grinding

LI, Ji-Tai* ; LIN, Zhi-Ping   

  1. (Hebei Key Laboratory of Analytical Science and Technology, College of Chemistry and Environmental Science,
    Hebei University, Baoding 071002)
  • Received:2007-11-18 Revised:2007-12-17 Published:2008-07-28
  • Contact: LI, Ji-Tai

蒙脱土K10固载ZnCl2是一个有效的环境友好催化剂. 在蒙脱土K10-ZnCl2催化下, 将吲哚与芳香醛混合在研钵中研磨2~8 min, 可得到收率为66%~97%的二吲哚甲烷衍生物. 该方法具有操作简便、反应条件温和、反应时间缩短、 对环境友好等优点.

关键词: 研磨, 蒙脱土K10-ZnCl2, 合成, 二吲哚甲烷

Montmorillonite K10-supported ZnCl2is an efficient and environmentally friendly catalyst. Reactions of aromatic aldehydes with indole catalyzed by montmorillonite K10-ZnCl2 afforded bis(indol-3-yl)- methanes in 66%~97% yields within 2~8 min by grinding. This method provided several advantages such as simple work-up procedure, shorter reaction time, milder conditions and environmental friendliness.

Key words: montmorillonite K10-ZnCl2, bis(indol-3-yl)methane, synthesis, grinding