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有机化学
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有机化学 ›› 2008, Vol. 28 ›› Issue (11): 1943-1947. 上一篇    下一篇

研究论文

2,6-二氨基-3,5-二硝基吡啶-1-氧化物的合成新方法

成 健a ; 姚其正b; 周新利a; 杜 扬a ; 方 东a; 刘祖亮*,a   

  1. (a南京理工大学化工学院 南京 210094)
    (b中国药科大学药学院 南京 210094)
  • 收稿日期:2008-04-01 修回日期:2008-04-28 发布日期:2008-11-18
  • 通讯作者: 刘祖亮

Novel Synthesis of 2,6-Diamino-3,5-dinitropyridine-1-oxide

CHENG, Jian a; YAO, Qi-Zheng b; ZHOU, Xin-Li a; DU, Yang a;
FANG, Dong a; LIU, Zu-Liang*,a
  

  1. (a School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094)
    (b School of Pharmacy, China Pharmaceutical University, Nanjing 210094)
  • Received:2008-04-01 Revised:2008-04-28 Published:2008-11-18
  • Contact: LIU, Zu-Liang

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被引次数

55 | 7

研究了2,6-二氨基-3,5-二硝基吡啶-1-氧化物(ANPyO)的合成新方法. 以2,6-二氨基吡啶为起始原料, 经酰基化、N-氧化、硝化三步反应得到ANPyO, 总收率为75%. 测试了ANPyO的爆速、爆压、DSC, 以及电火花感度和落锤感度, 同1,3,5-三氨基-2,4,6-三硝基苯(TATB)的性能进行了对比, 结果表明ANPyO综合性能和TATB基本相当. 用1H NMR, MS和红外光谱对ANPyO及其中间体结构进行了表征.

关键词: 2,6-二氨基-3,5-二硝基吡啶-1-氧化物, 1,3,5-三氨基-2,4,6-三硝基苯, 合成, 性能

A novel synthetic method of 2,6-diamino-3,5-dinitropyridine-1-oxide (ANPyO) was explored using 2,6-diaminopyridine as the starting materials in three steps, including acetylation, N-oxidation and nitration. Thus, the overall yield of ANPyO was up to 75%. Detonation velocity, detonation pressure, DSC and sensitivities of electrospark and impact for ANPyO were measured, showing that ANPyO and 1,3,5-triamino-2,4,6-trinitrobenzene (TATB) are almost equal in overall performance.

Key words: 1,3,5-triamino-2,4,6-trinitrobenzene, 2,6-diamino-3,5-dinitropyridine-1-oxide, synthesis, performance