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有机化学
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有机化学 ›› 2009, Vol. 29 ›› Issue (02): 302-306. 上一篇    下一篇

研究简报

N,N-二取代甘氨酸四乙酰基葡萄糖酯的合成与表征

李英俊* ; 刘 军 ; 许永廷 ; 靳 焜 ;
孙淑琴 ; 丁万刚; 刘丽军
  

  1. (a辽宁师范大学化学化工学院 大连116029)
    (b大连理工大学精细化工国家重点实验室 大连116012)
  • 收稿日期:2008-06-30 修回日期:2008-10-29 发布日期:2009-02-20
  • 通讯作者: 李英俊

Synthesis and Characterization of N,N-Disubstituted Glycine Tetraacetyl Glucosyl Esters

Li, Yingjun* ; Liu, Jun; Xu, Yongting; Jin, Kun;
Sun, Shuqin; Ding, Wangang; Liu, Lijun
  

  1. (a College of Chemistry and Chemical Engineering, Liaoning Normal University, Dalian 116029)
    (b State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012)
  • Received:2008-06-30 Revised:2008-10-29 Published:2009-02-20
  • Contact: Li, Yingjun

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1405

被引次数

8

在碳酸钾和十六烷基三甲基溴化铵存在下, 将N-(N-乙酰基-N-芳氨基乙酰基)-N-芳氨基乙酸与全乙酰化α-溴代葡萄糖反应合成出了7个新的N,N-二取代甘氨酸四乙酰基葡萄糖酯(5a～5g), 并利用IR, 1H NMR, MS和元素分析对其结构进行了表征.

关键词: 表征, 全乙酰化葡萄糖酯, N-(N-乙酰基-N-芳氨基乙酰基)-N-芳氨基乙酸, 合成

Seven new N,N-disubstituted glycine tetraacetyl glucosyl esters (5a～5g) were synthesized by the reaction of N-(N-acetyl-N-arylglycyl)-N-arylglycines with 2,3,4,6-tetra-O-acetyl-α-D-glucopyransoyl bromide in the presence of hexadecyltrimethyl ammonium bromide and potassium carbonate. The structures of the target compounds were characterized by IR, 1H NMR, MS techniques and elemental analysis.

Key words: N-(N-acetyl-N-arylglycyl)-N-arylglycine, synthesis, characteriza-tion, per-acetylated glucosyl ester