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有机化学
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有机化学 ›› 2009, Vol. 29 ›› Issue (03): 365-379. 上一篇    下一篇

综述与进展

嘧啶类化合物的合成及抗菌活性研究进展

吴 琴 ; 宋宝安*; 金林红 ; 胡德禹   

  1. (贵州大学精细化工研究开发中心 教育部绿色农药和生物工程重点实验室 贵阳 550025)
  • 收稿日期:2008-04-18 修回日期:2008-07-23 发布日期:2009-03-20
  • 通讯作者: 宋宝安

Research Advances in Synthesis and Antifungal Activity of Pyrimidine Compounds

Wu, Qin; Song, Baoan*; Jin, Linhong; Hu, Deyu   

  1. (Key Laboratory of Green Pesticide and Agriculture Bioengineering of Ministry of Education, Research and Development Center for Fine Chemicals, Guizhou University, Guiyang 550025)
  • Received:2008-04-18 Revised:2008-07-23 Published:2009-03-20
  • Contact: Song, Baoan

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被引次数

60 | 11

嘧啶类化合物因其广泛的生物活性在医药、农药等领域备受关注. 将不同基团引入嘧啶结构中, 经过结构修饰能产生一系列具有抗菌活性的嘧啶衍生物, 它在新型农药创制中发挥着越来越重要的作用. 对嘧啶类化合物的合成及杀菌活性的研究进行了分类综述, 并展望了它的发展趋势和应用前景.

关键词: 嘧啶, 合成, 抗菌活性

Pyrimidine compounds have been the subject of much attention in pesticide and medicine fields owing to their unique biological properties. In addition, the introduction of different groups into pyrimidine structures can generate a series of pyrimidine compounds with antifungal activity, which have played an important role in pesticide application. The synthesis and antifungal activity research for pyrimidine compounds are reviewed. The developing trends and application prospects of pyrimidine compounds are also discussed.

Key words: synthesis, antifungal activity, pyrimidine