SIOC English
有机化学
高级检索

有机化学 ›› 2009, Vol. 29 ›› Issue (07): 1152-1157. 上一篇    下一篇

研究简报

α-(2,4-二氯苯氧基乙酰氧基)-α-芳甲基膦酸酯的合成、 晶体结构及除草活性

王 涛a; 贺红武b ; 缪方明*,c   

  1. (a江西师范大学化学化工学院 南昌 330022)
    (b华中师范大学化学学院有机合成研究所 武汉 430079)
    (c天津师范大学晶体化学研究所 天津 300073)
  • 收稿日期:2008-11-03 修回日期:2009-01-05 发布日期:2009-07-22
  • 通讯作者: 缪方明

Synthesis, Crystal Structure and Herbicidal Activity of α-(2,4- Dichlorophenoxyacetoxy)-α-arylmethylphosphonates

Wang, Taoa ; He, Hongwub ; Miao, Fangming*,c   

  1. (a College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022)
    (b Institute of Organic Synthesis, Central China Normal University, Wuhan 430079)
    (c Institute of Crystal Chemistry, Tianjin Normal University, Tianjin 300073)
  • Received:2008-11-03 Revised:2009-01-05 Published:2009-07-22
  • Contact: Miao, Fangming

PDF

1294

被引次数

9

通过2,4-二氯苯氧基乙酰氯和α-羟基芳甲基膦酸酯的缩合反应合成了12种标题化合物, 用元素分析, IR, 1H NMR及MS作了表征. 为进一步了解此类化合物的结构, 用X射线单晶衍射测定了化合物4a的晶体结构. 初步的生物活性测试表明, 部分化合物对单、双子叶植物根的生长具有优异的抑制作用. 质量浓度分别为100和10 mg/L时, 化合物4a～4l对油菜根和稗草根的生长抑制率均超过90%.

关键词: 芳烷基膦酸酯, 合成, 生物活性, 晶体结构

Twelve novel α-(2,4-dichlorophenoxyacetoxy)arylmethylphosphonates were synthesized from the intermediate (α-hydroxyl)-α-arylmethylphosphonates and 2,4-dichlorophenoxyacetyl chloride. All com-pounds synthesized were identified by 1H NMR, IR and MS techniques. The crystal structure of the com-pound 4a was determined by X-ray single-crystal diffraction. Preliminary bioassay results showed that some of these compounds had better inhibiting effect against the roots of rape and barnyard grass. Inhibitory rates of compounds 4a～4l against the roots of rape and barnyard grass were more than 90% at a dosage of 100 and 10 mg/L respectively.

Key words: crystal structure, synthesis, bioactivity, arylmethylphosphonate