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有机化学
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有机化学 ›› 2010, Vol. 30 ›› Issue (01): 128-131. 上一篇    下一篇

研究简报

锦灯笼果实的化学成分研究

李 坤，刁云鹏，王明东，杨松松，张厚利，黄珊珊，杨 红*   

  1. (a辽宁师范大学生命科学学院 大连 116029) 
    (b大连医科大学药学院 大连 116044)
     (c辽宁中医药大学药学院 大连 116001)
  • 收稿日期:2009-03-03 修回日期:2009-07-13 发布日期:2010-01-20
  • 通讯作者: 刁云鹏 E-mail:diaoyp@163.com

Chemical Constituents of the Fruits of Physalis Alkekengi L。var。franchetii (Mast.) Makino

Li,Kun，Diao,Yunpeng，Wang,Mingdong，Yang,Songsong，Zhang,Houli，Huang,Shanshan，Yang,Hong*   

  1. (a College of Life Sciences，Liaoning Normal University，Dalian 116029) 
    (b College of Pharmacy，Dalian Medical University，Dalian 116044) 
    (c College of Pharmacy，Liaoning University of Traditional Chinese Medicine，Dalian 116001)
  • Received:2009-03-03 Revised:2009-07-13 Published:2010-01-20

PDF

1446

被引次数

15

从锦灯笼中分离得到5个甾体类化合物，分别鉴定为酸浆素A (1，alkekengilin A)、酸浆素B (2，alkekengilin B)、酸浆苦素D (3，physalin D)、酸浆苦素P (4，physalin P)、4,7-二去氢新酸浆苦素B (5，4,7-didehydro-neophysalin B)。其中酸浆素A (1，alkekengilin A)和酸浆素B (2，alkekengilin B)为新的天然产物。运用现代波谱技术对上述化合物的结构进行了确证。

关键词: 锦灯笼, 化学成分, 酸浆素, 酸浆苦素

Five compounds were isolated from the fruits of Physalis alkekengi L。var。franchetiI (Mast.) by silica gel column，D101 macroporous column，Sephadex LH-20 column，ODS column chromatography and HPLC。On the basis of the chemical and spectral methods，the structures of the five compounds were elucidated as alkekengilin A (1)，alkekengilin B (2)，physalin D (3)，physalin P (4) and 4,7-didehydro-neophysalin B (5)。Among these compounds，1 and 2 are two new compounds，and others are known compounds。

Key words: Physalis alkekengi L。var。franchetiI (Mast.) Makino, chemical constituent, alkekengilin, physalin