SIOC English
有机化学
高级检索

有机化学 ›› 2010, Vol. 30 ›› Issue (03): 456-460. 上一篇    下一篇

研究简报

(苯并呋喃-2-酰基)二茂铁衍生物的合成与表征

高文涛*，程秀萍，李阳   

  1. (渤海大学超精细化学品研究所 辽宁省应用化学重点试验室 锦州 121000)
  • 收稿日期:2009-04-18 修回日期:2009-07-23 发布日期:2010-03-28
  • 通讯作者: 高文涛 E-mail:isfc@bhu.edu.cn

Synthesis and Characterization of Novel (Benzo[b]furan-2- oyl)ferrocene Derivatives

Gao Wentao*,Cheng Xiuping,Li Yang   

  1. (Liaoning Key Laboratory of Applied Chemistry, Institute of Superfine Chemicals, Bohai University, Jinzhou 121000)
  • Received:2009-04-18 Revised:2009-07-23 Published:2010-03-28

PDF

1108

被引次数

15 | 2

氯乙酰基二茂铁(1)与水杨醛或取代水杨醛在聚乙二醇-400作相转移催化剂条件下, 使Williamson反应与Knoevenagel反应在一锅内完成, 以40.2%～70.0%的总收率得到了由羰基相连的二茂铁与苯并呋喃组成的结构新颖的闭环产物(苯并[b]呋喃-2-酰基)二茂铁衍生物2a～2n. 通过IR, 1H NMR, MS和元素分析确认了所合成新化合物2a～2n的结构.

关键词: 氯乙酰基二茂铁, 苯并呋喃, 水杨醛, 合成, 表征

(Benzo[b]furan-2-oyl)ferrocene derivatives 2a～2n were synthesized via Williamson reaction and Knoevenagel reaction between 1-chloroacetylferrocene and salicylaldehyde or substituted salicylaldehydes in a one-pot procedure with PEG-400 as phase transfer catalyst under mild conditions in 40.2%～70.0% yields. All the new compounds 2a～2n containing ferrocene and benzofuran backbones were fully characterized by IR, 1H NMR, MS techniques and elemental analysis.

Key words: chloroacetylferrocene, benzo[b]furan, salicylaldehyde, synthesis, characterization