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有机化学
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有机化学 ›› 2010, Vol. 30 ›› Issue (07): 1005-1009. 上一篇    下一篇

研究论文

一种新型双缩合螺吡喃的合成、表征及晶体结构

金丹*1，张峰2，张德纯3   

  1. (1皖南医学院药学系 芜湖 241002)
    (2昆山东方药业有限公司 昆山 215337)
    (3苏州大学化学化工学院 苏州 215006)
  • 收稿日期:2009-09-21 修回日期:2009-12-18 发布日期:2010-02-03
  • 通讯作者: 金丹 E-mail:jindande@126.com

Synthesis, Characterization and Crystal Structure of a Dicondensed Spiropyran

Jin Dan*1 Zhang Feng2 Zhang Dechun3   

  1. (1Department of Pharmacy, Wannan Medical College, Wuhu 241002) (2Kunshan Oriental Pharmaceutical Co., Ltd., Kunshan 215337) (3Department of Chemistry, Suzhou University, Suzhou 215006)
  • Received:2009-09-21 Revised:2009-12-18 Published:2010-02-03

PDF

1441

被引次数

23 | 4

以过量吲哚啉和5-硝基水杨醛为原料合成了4-(2-亚甲基-1-乙基-3,3-二甲基吲哚啉-2 -基)-6-硝基-1 -乙基-3 ,3 -二甲基-螺[3,4-二氢-2H-l-苯并吡喃-2,2 -吲哚啉], 通过核磁共振、红外光谱、元素分析对其结构进行了表征. 同时利用X单晶衍射仪测定了该化合物的结构, 结果表明: 晶体属单斜晶系, 空间群P2/n, a＝1.2476(3) nm, b＝1.1939(2) nm, c＝2.0317(4) nm, α＝90°, β＝107.45(3)°, γ＝90°, D＝1.205 g/cm, μ＝0.077 mm, F(000)＝1120, V＝2.8871(10) nm, Z＝4.

关键词: 双缩合螺吡喃, 表征, 晶体结构

A compound of 4-(2-methylene-1-ethyl-3,3-dimethylindoline-2 -yl)-6-nitryl-1 -ethyl-3 ,3 -di- methylspiro[3,4-dihydro-2H-1-benzopyran-2,2 -indoline] has been synthesized by the reaction of excess indoline with 5-nitrosalicylaldehyde in refluxing ethanol. The molecular structure was characterized by 1H NMR, IR spectra and elemental analysis. Meanwhile, the crystal of the compound was obtained and determined by X-ray diffraction study. Crystal data for this compound: monoclinic, space group P2/n, a＝1.2476(3) nm, b＝1.1939(2) nm, c＝2.0317(4) nm, α＝90°, β＝107.45(3)°, γ＝90°, D＝1.205 g/cm, μ＝0.077 mm, F(000)＝1120, V＝2.8871(10) nm, Z＝4.

Key words: dicondensed spiropyran, characterization, crystal sructure