有机化学 ›› 2010, Vol. 30 ›› Issue (10): 1508-1511. 上一篇    下一篇

研究论文

富勒烯半胱氨酸的固相合成与荧光特性

解馨,杨新林   

  1. (北京理工大学生命科学与技术学院 北京 100081)
  • 收稿日期:2009-11-21 修回日期:2010-04-27 发布日期:2010-05-28
  • 通讯作者: 杨新林 E-mail:xlyang@bit.edu.cn
  • 基金资助:

    国家级.国家自然科学基金

Solid-Phase Synthesis and Fluorescent Property of A Fullerene Cystine Derivative

JIE Xin, YANG Xin-Lin   

  1. (School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081)
  • Received:2009-11-21 Revised:2010-04-27 Published:2010-05-28

基于氨基与富勒烯之间的加成反应与多肽的固相有机合成, 合成了一种单加成富勒烯半胱氨酸(fullerene cystine, Fcy). 采用有机溶剂交换法制备了Fcy的纳米颗粒水悬液n-Fcy, 并比较了Fcy与n-Fcy的荧光性质.

关键词: 富勒烯氨基酸, 固相合成, 纳米颗粒水悬液, 荧光性质

A new mono-amino acid fullerene derivative fullerene cystine (Fcy) was synthesized for the first time, based on the addiction reaction between amino group and fullerene cage in combination with solid-phase polypeptide synthesis. An aqueous nanoparticle suspension of Fcy (denoted as n-Fcy) was then prepared by the method of organic solvent exchange, and the fluorescent properties of Fcy and n-Fcy were compared.

Key words: fullerene amino acid, solid-phase synthesis, aqueous nanoparticle suspension, fluorescent property