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有机化学
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有机化学 ›› 2011, Vol. 31 ›› Issue (02): 242-245. 上一篇    下一篇

研究简报

微波辐射下合成5-芳亚甲基-2,3-二芳基-4-噻唑啉酮类化合物

孙小军*，周建峰，朱惠琴   

  1. (淮阴师范学院化学化工学院 淮安 223300)
  • 收稿日期:2010-07-16 修回日期:2010-09-19 发布日期:2010-10-08
  • 通讯作者: 孙小军 E-mail:sunxiaojun100@126.com

Synthesis of 5-Arylidene-2,3-diaryl-4-thiazolidinones under Microwave Irradiation

SUN Xiao-Jun, ZHOU Jian-Feng, ZHU Hui-Qin   

  1. (School of Chemistry and Chemical Engineering, Huaiyin Normal University, Huaian 223300)
  • Received:2010-07-16 Revised:2010-09-19 Published:2010-10-08
  • Contact: 孙小军 SUN Xiao-Jun E-mail:sunxiaojun100@126.com

PDF

1542

被引次数

25 | 3

在水介质中, 以四丁基溴化铵(TBAB)作催化剂, 微波辐射下使芳醛与4-噻唑啉酮反应合成一系列5-芳亚甲 基-2,3-二芳基-4-噻唑啉酮类化合物. 该反应具有反应时间短、产率高、环境友好、后处理简便等优点. 所有化合物均经IR, MS, 1H NMR和元素分析确定. 同时用X射线衍射法测定了化合物4a的晶体结构.

关键词: 芳香醛, 4-噻唑啉酮, 微波辐射

A series of new 5-arylidene-2,3-diaryl-4-thiazolidinone derivatives were synthesized by the reaction of aromatic aldehydes with 4-thiazolidinone using TBAB as catalyst in aqueous media under microwave irradiation. The procedure has the advantages of short reaction time, high yield, environmental benign and easy workup. Their structures were confirmed by 1H NMR, IR, MS techniques and elemental analysis, and compound 4a was analyzed by X-ray single-crystal diffraction.

Key words: aromatic aldehyde, 4-thiazolidinone, microwave irradiation, crystal structure