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有机化学
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有机化学 ›› 2001, Vol. 21 ›› Issue (10): 742-745. 上一篇    下一篇

研究论文

微波辐射一步法合成吡喃和吡喃[2, 3-c]吡唑衍生物

周建峰;屠树江;高原;嵇明   

  1. 淮阴师范学院化学系;徐州师范大学化学系.徐州(221009);深圳大学师范学院 化生系.
  • 发布日期:2001-10-25

One pot synthesis of pyrans and pyrano[2, 3-c] pyrazole derivatives under microwave irradiation

Zhou Jianfeng;Tu Shujiang;Gao Yuan;Ji Ming   

  1. Xuzhou Teachers Coll, Dept Chem.Xuzhou(221009);Shenzhen.
  • Published:2001-10-25

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600

被引次数

39 | 11

芳醛、丙二腈与5,5-二甲基-1,3-环己二酮或3-甲基-1-苯基-2-吡唑啉-5-酮在乙醇溶剂中用哌啶作催化剂，经微波辐射一步合成了2-氨基-3-氰基-4-芳基-7,7-二甲基-5-氧代-5,6,7,8-四氢苯并吡喃和6-氨基-5-氰基-4-芳基-1,4-二氢吡喃[2,3-c]吡唑，反应在2～12min内完成，产率53%～91%。

关键词: 微波辐射, 吡喃P, 环己二酮, 吡唑啉P, 丙二腈, 哌啶, 吡唑P, 苯并吡喃P, 一步法(化工)

2-Amino-3-cycano-4-aryl-7, 7-dimethyl-5, 6, 7, 8- tetrehydrobenzo[b] pyrans and 6-amino-5-cyano-4-aryl- 1, 4-dihydropyrano[2, 3-c]pyrazoles were synthesized by one-step reaction of aromatic aldehydes, malononitrile and dimedone or 3-methyl-1-phenyl-2-pyrazolin-5-one usig piperidine as catalyst under microwave irradiation. The reactions were completed in 2～12 min in good yields.

Key words: MICROWAVE RADIATION, PYRANE P, CYCLOHEXANEDIONE, PYRAZOLINE P, PROPANEDINITRILE, PIPERIDINE, PYRAZOLE P, BENZOPYRAN P, ONE-STEP PROCESS

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