有机化学 ›› 1999, Vol. 19 ›› Issue (5): 489-494. 上一篇    下一篇

研究论文

二苄基一氯化锡氨荒酸酯的合成与表征

尹汉东;马春林;张如芬;王勇   

  1. 山东省聊城师范学院化学系
  • 发布日期:1999-10-25

Synthesis and characterization of chlorodibenzyltin dithiocarbamates

Yin Handong;Ma Chunlin;Zhang Rufen;Wang Yong   

  • Published:1999-10-25

合成了13个新的二苄基一氯化锡氨荒酸酯化合物(PhCH~2)~2Sn(Cl)Sn(Cl)S~2CNRR'。利用元素分析、UV、IR、^1HNMR谱和TG-DTA表征了它们的结构。初步生物活性研究表明,有些化合物表现出体外抑制白血细胞P~3~8~8生长的活性。

关键词: 表征, 氨荒酸酯, 生物活性, 有机锡化合物, 合成

Thirteen new chlorodibenzyltin dithiocarbamates (PhCH~2)~2Sn(Cl) S~2CNRR' were synthesized and characterized by elemental analysis, UV, IR, ^1H NMR spectroscopy and TG-DTA. Preliminary biological activity test showed that some of them have remarkable activity against P~3~8~8 cells in vitro.

Key words: SYNTHESIS, CHARACTERIZATION, BIOLOGICAL ACTIVITY, ORGANO TIN COMPOUNDS

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