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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (10): 1278-1281. 上一篇    下一篇

研究简报

N'-(4,6-二取代嘧啶-2-基)氧化烟酰硫脲的合成与生物活性测定

李景智，薛思佳*，郭彦玲   

  1. (上海师范大学生命与环境科学学院 上海 200234)
  • 收稿日期:2006-01-11 修回日期:2006-04-20 发布日期:2007-09-28
  • 通讯作者: 薛思佳

Synthesis and Biological Activity of Oxidized Nicotinicacyl Thiourea Derivatives

LI Jing-Zhi,XUE Si-Jia*,GUO Yan-Ling   

  1. (College of Life and Environment Science, Shanghai Normal University, Shanghai 200234)
  • Received:2006-01-11 Revised:2006-04-20 Published:2007-09-28
  • Contact: XUE Si-Jia

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被引次数

1

合成并表征了9种未见文献报道的N'-(4,6-二取代嘧啶-2-基)氧化烟酰硫脲衍生物3, 结构经IR, 1H NMR, 元素分析得到确证. 初步的生物活性测试表明化合物3a具有较好的除草活性, 化合物3b具有一定的杀虫活性.

关键词: N'-(4,6-二取代嘧啶-2-基)-N-氧化烟酰硫脲, 2-氨基-4,6-二取代嘧啶, 生物活性, 合成

Nine new N'-(4,6-disubstituted pyrimidin-2-yl)-N-oxidized nicotinicacyl thiourea derivatives 3 have been synthesized and characterized. The structures of 3 were conformed by IR, 1H NMR spectra and elemental analysis. The preliminary biological tests showed that compound 3a has good herbicidal activities and compound 3b has good insecticidal activities.

Key words: 2-amino-4,6-disubstituted pyrimidine, synthesis, biological activity, N'-(4,6-disubstituted pyrimidin-2-yl)-N-oxidized nicotinicacyl thiourea