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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (10): 1305-1308. 上一篇    

研究简报

2-薁基取代的苯并[b]呋喃类化合物的合成

王道林*，徐姣，韩珊，谷峥   

  1. (渤海大学化学化工学院 辽宁省应用化学重点实验室 锦州 121003)
  • 收稿日期:2006-10-09 修回日期:2007-03-13 发布日期:2007-09-28
  • 通讯作者: 王道林

Synthesis of 2-Azulen-2'-ylbenzo[b]furan Derivatives

WANG Dao-Lin*,XU Jiao,HAN Shan,GU Zheng   

  1. (Liaoning Key Laboratory of Applied Chemistry, College of Chemistry and Chemical Engineer-ing,
    Bohai University, Jinzhou 121003)
  • Received:2006-10-09 Revised:2007-03-13 Published:2007-09-28
  • Contact: WANG Dao-Lin

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以溴代丁二酰亚胺为溴化试剂, 对1-氰基-2-甲基薁进行了溴代反应研究, 将溴甲基化产物与水杨醛类衍生物在通常的加热反应及微波辐射条件下进行缩合, 以较高的收率得到2-薁基取代苯并[b]呋喃, 其结构经1H NMR, IR及元素分析等得以证实.

关键词: 薁, 苯并[b]呋喃, 合成, 微波辐射

2-Azulen-2'-ylbenzo[b]furans were obtained via coupling reaction of 2-bromomethylazulene with salicylaldehydes under thermal and microwave irradiation conditions. The bromination conditions of 1-cyano-2-methylazulene with N-bromosuccinimide were discussed. All the compounds were fully characterized by 1H NMR, IR spectra and elemental analysis.

Key words: benzo[b]furan, salicylaldehyde, microwave irradiation, synthesis, azulene