有机化学 ›› 2008, Vol. 28 ›› Issue (01): 137-140. 上一篇    下一篇

研究简报

手性方酰化哒嗪衍生物的合成及荧光特性研究

熊俊如*,陈稼轩,向清祥,张元勤   

  1. (乐山师范学院化学与生命科学系 乐山 614004)
  • 收稿日期:2007-02-22 修回日期:1900-01-01 发布日期:2008-01-23
  • 通讯作者: 熊俊如

Synthesis and Fluorescence of Chiral Pyridazine Derivatives ofSquaric Acid

XIONG Jun-Ru*, CHEN Jia-Xuan, XIANG Qing-Xiang, ZHANG Yuan-Qin   

  1. (Department of Chemistry and Life Science, Leshan Teachers College, Leshan 614004)
  • Received:2007-02-22 Revised:1900-01-01 Published:2008-01-23
  • Contact: XIONG Jun-Ru

以3,6-二甲酰基哒嗪和丙氨酸、α-氨基苯酚、方酸为原料合成了一种新的手性方酰化哒嗪胺衍生物, 利用IR, 1H NMR及元素分析对其结构进行了表征, 并研究了金属离子对化合物的荧光性的影响. 结果表明, Cu2+, Ni2+等金属离子对化合物产生明显的荧光猝灭作用.

关键词: 手性方酰化丙氨酸甲酯, 离子识别, 哒嗪衍生物, 合成, 荧光猝灭, 荧光性

The new chiral N,N'-bis(squaryl)-3,6-pyridazinrlene bis(methylamine) has been synthesized by the reaction 3,6-diformylpyridazine with methyl lactamate, o-aminophenol and squaric acid. The structures of the new compound and its intermediates were confirmed by IR, 1H NMR spectra and elemental analysis. The effect of metal ions on the fluorescence characteristics of the compound was also investigated. The selective interaction between metal ions (Cu2+, Ni2+) and the compound led to obvious fluorescence quenching.

Key words: pyridazine derivative, chiral methyl N-squaryl lactamate, synthesis, ion recognition, fluorescence quenching, fluorescence