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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (01): 60-64. 上一篇    下一篇

研究论文

含有脲桥结构的双酰肼衍生物的合成和杀虫活性研究

毛春晖1,2，汪清民*,1，欧晓明2，黄润秋1，陈莉1
尚坚1，毕富春1   

  1. (1南开大学元素有机化学研究所元素有机化学国家重点实验室 天津 300071)
    (2湖南化工研究院 国家南方农药创制中心湖南基地 长沙 410007)
  • 收稿日期:2005-03-01 修回日期:2005-07-18 发布日期:2005-12-31
  • 通讯作者: 汪清民

Synthesis and Insecticidal Evaluation of N,N-DiacylhydrazineDerivatives Containing the Urea Linkage

MAO Chun-Hui1,2,WANG Qing-Min*,1,OU Xiao-Ming2,HUANG Run-Qiu1
CHEN Li1,SHANG Jian1,BI Fu-Chun1   

  1. (1 State Key Laboratory of Elemento-organic Chemistry, Research Institute of Ele-mento-organic Chemistry,
    Nankai University, Tianjin 300071)
    (2 Hunan Branch of National Pesticide Research and Development South Center, Hunan Research Institute of
    Chemical In-dustry, Changsha 410007)
  • Received:2005-03-01 Revised:2005-07-18 Published:2005-12-31
  • Contact: WANG Qing-Min

PDF

1751

被引次数

16

经2,6-二氟苯甲酰基异氰酸酯(或异氰酸苯酯)与N-叔丁基-N-取代苯甲酰肼(或苯环上含有氨基的双酰肼化合物)反应得到一系列含有脲桥结构的双酰肼类化合物, 生测结果表明部分目标化合物具有好的杀幼虫活性. 例如, 化合物IIa和IIe, 药剂浓度为0.02%, 杀幼虫活性分别为95%和100%.

关键词: 双酰肼化合物, 杀幼虫活性, 昆虫生长调节剂, 蜕皮, 脲桥

A series of novel N,N-diacylhydrazine derivatives containing the urea linkage were synthesized by the reaction of 2,6-difluorobenzoyl isocyanate (or isocyanatobenzene) with N-tert-butyl-N-substituted benzoylhydrazine or N,N-diacylhydrazines containing amino group in 1,2-dichloroethane under reflux. The results of bioassay showed that some of the title compounds exhibit good larvicidal activities. For ex-ample, the larvicidal activities of derivatives IIa and IIe to Oritental armyworm at the concentration of 0.02% were 95% and 100%, respectively.

Key words: insect growth regulator, larvicidal activity, urea linkage, exuviation, diacylhydrazine