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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (01): 56-59. 上一篇    下一篇

研究论文

三个新的海绵Spongia suriganensis神经酰胺

徐石海*，杨凯   

  1. (暨南大学生命科学技术学院 广州 510632 )
  • 收稿日期:2005-02-21 修回日期:2005-07-11 发布日期:2005-12-31
  • 通讯作者: 徐石海

Three New Ceramides from the Sponge Spongia suriganensis

XU Shi-Hai*,YANG Kai   

  1. (Life Science College of Jinan University, Guangzhou 510632)
  • Received:2005-02-21 Revised:2005-07-11 Published:2005-12-31
  • Contact: XU Shi-Hai

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报道从中国南海硇洲岛产海绵Spongia suriganensis的乙醇浸提物中分离得到3个新的同系列神经酰胺2-N-(1,3,4-三羟基-17-甲基)十八烷基-2'-羟基-18-甲基二十碳酰胺(1), 2-N-(1,3,4-三羟基-17-甲基)十八烷基-2'-羟基-19-甲基二十一碳酰胺(2)和2-N-(1,3,4-三羟基-17-甲基)十八烷基-2'-羟基-20-甲基二十二碳酰胺(3), 其结构经过MS, IR, 1H NMR, 13C NMR (DEPT), HMQC及HMBC等现代光谱手段和水解化学方法来确定.

关键词: 海绵, Spongia suriganensis, 神经酰胺

Three new isomeric ceramides, 2-hydroxy-N-(1,3,4-trihydroxy-17-methyloctadecan-2-yl)-18- methylarachidamide (1), 2-hydroxy-N-(1,3,4-trihydroxy-17-methyloctadecan-2-yl)-19-methylhenei-cosanamide (2) and 2-hydroxy-N-(1,3,4-trihydroxy-17-methyloctadecan-2-yl)-20-methylbehenamide (3), were isolated from Spongia suriganensis collected from the China South Sea. Their structures were confirmed by spectroscopic analysis and hydrolysis.

Key words: spongia suriganensis, ceramide, sponge