SIOC English
有机化学
高级检索

有机化学 ›› 2005, Vol. 25 ›› Issue (08): 994-996. 上一篇    下一篇

研究简报

分子筛固载氟化钾催化芳香醛与环酮的缩合反应

杨文智*，李海鹰，黄顺升，李记太，王书香，曹玉庆   

  1. (河北大学药学院 保定 071002)
  • 收稿日期:2004-10-10 修回日期:2005-02-02 发布日期:2005-07-30
  • 通讯作者: 杨文智

Synthesis of α,α'-Dibenzylidenecycloalkanones Catalyzed by KF Supported on Molecular Sieve

YANG Wen-Zhi*,LI Hai-Ying,HUANG Shun-Sheng
LI Ji-Tai,WANG Shu-Xiang,CAO Yu-Qing   

  1. (College of Pharmacy, Hebei University, Baoding 071002)
  • Received:2004-10-10 Revised:2005-02-02 Published:2005-07-30
  • Contact: YANG Wen-Zhi

PDF

2241

被引次数

41

在回流甲醇条件下, 使用分子筛固载氟化钾催化芳醛与环己酮或环戊酮的缩合, 反应80～480 min, 获得56%～95% 产率的α,α'-二取代苯叉环烷酮.

关键词: 分子筛固载氟化钾, Claisen-Schmidt缩合, α,α'-二取代苯叉环烷酮

Claisen-Schmidt condensation of cyclopentanone or cyclohexanone with aromatic aldehydes catalyzed by potassium fluoride supported on molecular sieve resulted in 2,5-bis(substituted benzylidene)cyclopentanones or 2,6-bis(substituted benzylidene)cyclohexanones with 56%～95% yields respectively under refluxing methanol for 80～480 min.

Key words: KF supported on molecular sieve, Claisen-Schmidt condensation, α,α'-dibenzylidenecyclo