有机化学 ›› 2007, Vol. 27 ›› Issue (01): 120-122. 上一篇    下一篇

研究简报

无溶剂条件下芳香醛与氯代苯乙酮的Darzens 缩合反应

李磊,任仲皎*,曹卫国,黄培刚,朱华   

  1. (上海大学化学系 上海 200444)
  • 收稿日期:2006-04-25 修回日期:2006-06-05 发布日期:2006-12-30
  • 通讯作者: 任仲皎

Solvent-Free Darzens Condensation Reaction of AromaticAldehydes with Phenacyl Chloride by Grinding

LI Lei,REN Zhong-Jiao*,CAO Wei-Guo,HUANG Pei-Gang,ZHU Hua   

  1. (Department of Chemistry, Shanghai University, Shanghai 200444)
  • Received:2006-04-25 Revised:2006-06-05 Published:2006-12-30
  • Contact: REN Zhong-Jiao

在无溶剂、氢氧化钠的作用下, 用研磨的方法、通过Darzens缩合反应制备环氧化合物. 它的优点是操作简单、反应条件温和、产率高和环境污染小.

关键词: Darzens反应, 环氧化合物, 无溶剂, 研磨

A solvent-free Darzens condensation reaction for the preparation of epoxide compounds in the presence of NaOH by grinding was achieved. Its advantages are easy work-up, mild reaction condition, high yield and environmental compatibility.

Key words: Darzens reaction, epoxide compound, grinding process, solvent-free