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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (9): 1272-1274. 上一篇    下一篇

研究简报

离子液体/水混合溶剂促进芳醛与罗丹宁的缩合反应

练习中，李毅群*，周美云   

  1. (暨南大学化学系 广州 510632)
  • 收稿日期:2005-11-09 修回日期:2005-12-07 发布日期:2006-09-11
  • 通讯作者: 李毅群

onic Liquid/H2O System Promoted Condensation ofAromatic Aldehydes and Rhodanine

LIAN Xi-Zhong,LI Yi-Qun*,ZHOU Mei-Yun   

  1. (Department of Chemistry, Jinan University, Guangzhou 510632)
  • Received:2005-11-09 Revised:2005-12-07 Published:2006-09-11
  • Contact: LI Yi-Qun

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被引次数

13 | 2

在室温条件下, 离子液体1-正丁基-3-甲基咪唑四氟硼酸盐([bmim]BF4)与水组成的混合溶剂能有效催化一系列芳醛与罗丹宁反应, 以80%～93%的产率生成相应的5-芳亚甲基-2,4-噻唑二酮. 离子液体[bmim]BF4催化活性高, 反应在10～120 min内完成. 实验结果表明该法反应条件温和、产率高、反应时间短、后处理简单、离子液体可重复使用.

关键词: 罗丹宁, 5-芳亚甲基-2,4-噻唑二酮, 离子液体, 芳醛

The mixed solvent of ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate and water has efficiently promoted the synthesis of a variety of 5-arylmethylidene-4-oxo-2-thiothiazolidines from the corresponding aromatic aldehydes and rhodanine at room temperature in 80%～93% yields within 10 to 120 min. The present protocol offered several advantages including mild conditions, high yields, short reaction time, and simple work-up procedure. Moreover, the ionic liquid was reusable.

Key words: rhodanine, 5-arylmethylidene-4-oxo-2-thiothiazolidine, aryl aldehyde, ionic liquid