有机化学 ›› 2012, Vol. 32 ›› Issue (9): 1666-1672.DOI: 10.6023/cjoc201206029 上一篇    下一篇

研究论文

钯/碳高效绿色催化Suzuki交叉偶联反应

初文毅a,b, 王熳a,b, 李新民a,b, 侯艳君a,b, 孙志忠a,b   

  1. a 黑龙江大学化学化工与材料学院 哈尔滨 150080;
    b 黑龙江省普通高等学校高效转化的化工过程与技术重点实验室 哈尔滨 150080
  • 收稿日期:2012-06-30 修回日期:2012-07-18 发布日期:2012-07-14
  • 通讯作者: 孙志忠 E-mail:sunzz@hlju.edu.cn
  • 基金资助:

    黑龙江省教育厅科技(No.12511383)和哈尔滨市科技局科技创新人才研究专项基金(No.RC2012XK001005)资助项目

Pd/C-Catalyzed Highly Efficient and Green Suzuki Cross-Coupling Reaction

Wang Mana,b, Li Xinmina,b, Hou Yanjuna,b, Sun Zhizhonga,b   

  1. a School of Chemistry and Materials Science, Heilongjiang University, Harbin 150080;
    b Key Laboratory of Chemical Engineering Process & Technology for High-efficiency Conversion, College of Heilongjiang Province, Harbin 150080
  • Received:2012-06-30 Revised:2012-07-18 Published:2012-07-14
  • Supported by:

    Project supported by the Research Project of Education Department of Heilongjiang Province of China (No.12511383) and the Research Special Funds for Innovation Talent of Harbin of China (No.RC2012XK001005)

开发了一个以钯/碳为催化剂高效绿色催化Suzuki反应制备联苯类化合物的新方法.该体系以环境友好的聚乙二醇400的水溶液为反应溶剂,加入离子液体1-甲基-3-丁基咪唑双三氟甲磺酰亚胺盐,可高效催化溴代芳烃与芳基硼酸的Suzuki交叉偶联反应,并且催化剂可以循环利用4次而催化效率没有明显降低.

关键词: 钯/碳, Suzuki 反应, 联苯类化合物, 离子液体

An efficient protocol for the Suzuki reaction catalyzed by Pd/C has been developed in a green sovent. This method is able to prepare a variety of biaryls in high yields. In the presence of 1-butyl-3-methylimidazolium bis[(trifluoro-methyl)sulfonyl]imide, the cross-coupling reaction of aryl bromides with arylboronic acids proceed smoothly in PEG400 aqueous at 45℃. The catalyst could be recycled four times without loss of activity.

Key words: Pd/C, Suzuki reaction, biphenyls, ionic liquid