有机化学 ›› 2013, Vol. 33 ›› Issue (12): 2607-2611.DOI: 10.6023/cjoc201307042 上一篇    下一篇

研究简报

新型氮杂杯[4]吡啶[4]嘧啶的合成与晶体结构研究

杨梓君, 尹冲, 张琳萍, 钟毅, 徐红, 毛志平   

  1. 东华大学化学化工与生物工程学院 生态纺织教育部重点实验室 上海 201620
  • 收稿日期:2013-07-26 修回日期:2013-08-23 发布日期:2013-08-29
  • 通讯作者: 张琳萍, 毛志平 E-mail:zhang_lp@dhu.edu.cn;zhpmao@dhu.edu.cn
  • 基金资助:

    中央高校基本科研业务费专项基金(No. 13D110530)资助项目.

Synthesis and Crystal Structure of Azacalix[4]pyridine[4]pyrimidine

Yang Zijun, Yin Chong, Zhang Linping, Zhong Yi, Xu Hong, Mao Zhiping   

  1. Key Laboratory of Science & Technology of Eco-Textile, Ministry of Education, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620
  • Received:2013-07-26 Revised:2013-08-23 Published:2013-08-29
  • Supported by:

    Project supported by the Fundamental Research Funds for the Central Universities (No. 13D110530).

从简单易得的2,6-二溴吡啶、4,6-二氯嘧啶两种原料出发,通过钯催化的“2+2”片段偶联法,简捷有效地合成了一种新型氮杂杯[4]吡啶[4]嘧啶,产物结构通过IR,1H NMR,13C NMR和HRMS进行了表征;并培养得到了氮杂杯[4]吡啶[4]嘧啶的晶体,对其晶体结构进行了X射线单晶衍射分析.

关键词: 氮杂杯[4]吡啶[4]嘧啶, 合成, 表征, 晶体结构

A novel azacalix[4]pyridine[4]pyrimidine was synthesized by means of a [2+2] fragment coupling approach from 2,6-dibromopyridine and 4,6-dichloropyrimidine. The lead compound was characterized by 1H NMR, 13C NMR, IR and HRMS. The crystal structure was determined by X-ray diffraction method.

Key words: azacalix[4]pyridine[4]pyrimidine, synthesis, characterization, crystal structure