有机化学 ›› 2015, Vol. 35 ›› Issue (1): 246-250.DOI: 10.6023/cjoc201405039 上一篇    下一篇

研究简报

光照条件下链状醚α-碳-氢键官能团化反应研究

孙京a, 彭新华a, 郭浩b   

  1. a 南京理工大学化工学院 南京 210094;
    b 复旦大学化学系 上海 200433
  • 收稿日期:2014-05-29 修回日期:2014-08-11 发布日期:2014-09-09
  • 通讯作者: 彭新华, 郭浩 E-mail:xinhpeng@njust.edu.cn;hao_guo@fudan.edu.cn
  • 基金资助:

    教育部留学回国人员科研启动基金(No.【45-5】)资助项目.

Photoinduced α-C—H Bond Functionalization of Linear Ethers

Sun Jinga, Peng Xinhuaa, Guo Haob   

  1. a School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094;
    b Department of Chemistry, Fudan University, Shanghai 200433
  • Received:2014-05-29 Revised:2014-08-11 Published:2014-09-09
  • Supported by:

    Project supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry (No.【45-5】).

发展了一套新型的可以实现链状醚α-碳-氢键官能团化的方法. 该方法无需任何添加剂, 仅在紫外光的激发下, 室温下即可温和且高效地完成芳基醛、酮类化合物与链状醚类化合物的加成反应, 从而可以清洁且高选择性地生成β-羟基醚类化合物. 研究了激发光能量及反应温度对该反应的影响, 并对该反应可能的机理进行了讨论.

关键词: 光化学, 碳-氢键官能团化, 机理, 自由基反应, 绿色化学

A new and effective method for the direct functionalization of ethereal C—H bond was reported. This reaction undergoes smoothly under UV irradiation at room temprature without any additive, which presents a new environmentally friendly protocol to access β-hydroxyl ethers highly selectively. In addition, a possible mechanism of this reaction was proposed.

Key words: photochemistry, C-H functionalization, mechanism, radical reactions, green chemistry