关键词: 吡啶盐-氯胺前体, 多步合成, 全氟苯基叠氮化学, 抗菌聚氨酯膜, 抗菌性能

In this work, two novel pyridinium N-chloramine precursors were designed and synthesized, both of which contain perfluorophenyl azide (PFPA) unit as the photo-coupling handle. The synthetic precursors were photo immobilized on commercial PU films upon UV (254 nm) light irradiation. After exposure to diluted household bleach, the resulting PU films were rendered biocidal. Antibacterial tests showed that satisfactory was achieved for both surface modified films and that the film grafted with shorter alkyl linker-contained precursor demonstrated even higher biocidal efficacy. Non-leaching antibacterial PU materials were herein developed based on PFPA-coupling strategy, providing a simple and universal method to confer N-chloramines on inert polymer surface for antibacterial application.

Key words: pyridinium N-chloramine precursors, multi-step synthesis, fluorophenyl azide (PFPA) chemistry, biocidal polyurethane film, antimicrobial activity