有机化学 ›› 2022, Vol. 42 ›› Issue (1): 33-53.DOI: 10.6023/cjoc202107066 上一篇    下一篇

综述与进展

壳聚糖负载铜催化剂在有机反应中的应用研究进展

张瑶瑶a,*(), 周丽洁a,b, 韩彪a,b, 李维双a, 李博解a,*(), 朱磊a,b,c,*()   

  1. a 湖北工程学院化学与材料科学学院 湖北孝感 432000
    b 湖北大学材料科学与工程学院 武汉 430062
    c 华中科技大学生物无机化学与药物湖北省重点实验室 武汉 430074
  • 收稿日期:2021-07-31 修回日期:2021-09-11 发布日期:2021-09-26
  • 通讯作者: 张瑶瑶, 李博解, 朱磊
  • 基金资助:
    国家自然科学基金(21774029); 国家自然科学基金(22108065); 湖北省自然科学基金(2019CFB354); 湖北省高等学校优秀中青年科技创新团队计划(T201816); 孝感市自然科学计划(XGKJ2020010053); 孝感市自然科学计划(XGKJ2021010009)

Research Progress of Chitosan Supported Copper Catalyst in Organic Reactions

Yaoyao Zhanga(), Lijie Zhoua,b, Biao Hana,b, Weishuang Lia, Bojie Lia(), Lei Zhua,b,c()   

  1. a School of Chemistry and Materials Science, Hubei Engineering University, Xiaogan, Hubei 432000
    b School of Materials Science and Engineering, Hubei University, Wuhan 430062
    c Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica, Huazhong University of Science and Technology, Wuhan 430074
  • Received:2021-07-31 Revised:2021-09-11 Published:2021-09-26
  • Contact: Yaoyao Zhang, Bojie Li, Lei Zhu
  • Supported by:
    National Natural Science Foundation of China(21774029); National Natural Science Foundation of China(22108065); Natural Science Foundation of Hubei Province(2019CFB354); Young and Middle-Aged Science and Technology Innovation Team Project in Higher Education Institutions of Hubei Province(T201816); Natural Science Foundation of Xiaogan City(XGKJ2020010053); Natural Science Foundation of Xiaogan City(XGKJ2021010009)

壳聚糖是由甲壳素脱乙酰化而得, 是一种丰富可再生的生物质资源. 壳聚糖分子结构中含有大量的羟基、氨基, 与金属纳米粒子或金属离子具有较强的鳌合能力, 被广泛用作载体制备异相催化剂. 近年来, 壳聚糖负载铜催化剂被成功应用于各种不同类型的有机反应中, 不仅具有反应活性高、选择性好、易于分离回收等优点, 而且能够多次循环再利用, 在降低反应成本的同时, 也提升了实际的工业应用价值. 因此, 从不同类型壳聚糖负载铜催化剂的制备出发, 综述其催化的各种类型的有机反应, 主要涉及C—C键和C—X键的构建、点击化学及氧化还原反应等类型, 促进今后壳聚糖及其衍生物负载催化剂更加广泛的应用.

关键词: 壳聚糖负载铜催化剂, 有机反应, 异相催化, 绿色化学, 循环再利用

Chitosan is obtained by deacetylation of chitin and is a kind of abundant renewable biomass resource. The molecular structure of chitosan contains a large number of hydroxyl and amino groups, which have strong bonding ability with metal nanoparticles or metal ions. Thus it has been widely used to support various metal particles for the preparation of catalysts. In recent years, chitosan supported copper catalyst has been successfully applied in various types of organic reactions. It has the advantages of high reactivity, good selectivity, easy separation, and can also be reused for many times, which reduces the reaction cost and improves the actual industrial application value. Therefore, based on the preparation of different types of chitosan supported copper catalysts, various types of organic reactions are reviewed, mainly involving the constructions of C—C bond and C—X bond, click chemistry and oxidation/reduction reactions. It will promote the application of chitosan and its derivatives-supported catalysts in the future.

Key words: chitosan supported copper catalyst, organic reaction, heterogeneous catalysis, green chemistry, recycle and reuse