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有机化学
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有机化学 ›› 2004, Vol. 24 ›› Issue (5): 502-505. 上一篇    下一篇

研究论文

2,5-二取代芳基-1,3,4-噻二唑衍生物的微波法合成

黄华鸣, 于海涛, 陈培丽, 韩杰, 孟继本*   

  1. 南开大学化学系 天津 300071
  • 收稿日期:2003-04-21 修回日期:2003-09-22 接受日期:2003-11-07 发布日期:2022-09-20
  • 基金资助:
    国家自然科学基金(No. 20072018)资助项目.

Synthesis of 2,5-Diaryl-1,3,4-thiadiazoles via Lawesson's Reagent under Microwave Irradiation

HUANG, Hua-Ming, YU, Hai-Tao, CHEN, Pei-Li, HAN, Jie, MENG,Ji-Ben*   

  1. Department of Chemistry, Nankai University, Tianjin 300071
  • Received:2003-04-21 Revised:2003-09-22 Accepted:2003-11-07 Published:2022-09-20
  • Contact: *E-mail: mengjiben@nankai.edu.cn

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在微波辐射下,Lawesson试剂与相应的二芳基甲酰肼反应,生成2,5-二芳基-1,3,4-噻二唑衍生物.反应时间短,产率高.所有产物结构经1H NMR, IR, MS和元素分析确认.

关键词: Lawesson试剂, 微波反应, 1,3,4-噻二唑, 合成

2,5-Diaryl-1,3,4-thiadiazoles were prepared in 74%～91% yields via Lawesson's reagent (LR) under microwave irradiation without solvent. The structures of the compounds were confirmed by 1H NMR, IR, MS and elemental analyses.

Key words: Lawesson's reagent, microwave-assisted reaction, thiadiazole, synthesis