Microwave Assisted Solvent-Free Synthesis of 3-(Trifluoroacetyl)coumarins

doi:10.6023/cjoc201411012

Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (5): 1173-1178.DOI: 10.6023/cjoc201411012 Previous Articles Next Articles

Notes

微波辅助无溶剂合成3-三氟乙酰基香豆素类化合物

杨国玉, 王彩霞, 樊素芳, 谢普会, 金秋, 徐翠莲

河南农业大学理学院郑州 450002

收稿日期:2014-11-08 修回日期:2014-12-13 发布日期:2015-01-06
通讯作者: 徐翠莲 E-mail:xucuilian666@126.com
基金资助:
河南省教育厅基金(Nos.2009A150012,2011A210018)、国家自然科学基金(No.21102037)、河南省科技攻关项目基金(No.112101110200)资助项目.

Microwave Assisted Solvent-Free Synthesis of 3-(Trifluoroacetyl)coumarins

Yang Guoyu, Wang Caixi, Fan Sufang, Xie Puhui, Jin Qiu, Xu Cuilian

College of Sciences, Henan Agricultural University, Zhengzhou 450002

Received:2014-11-08 Revised:2014-12-13 Published:2015-01-06
Supported by:
Project supported by the Education Foundation of Henan Province (Nos.2009A150012, 2011A210018), the National Natural Science Foundation of China (No.21102037), and the Key Science and Technology Foundation of Henan Province (No.112101110200).

1. Microwave Assisted Solvent-Free Synthesis of 3-(Trifluoroacetyl)coumarins.PDF(1562KB)

Abstract

A series of 3-(trifluoroacetyl)coumarins were synthesized by recyclization of ethyl-2-hydroxy-2-trifluoromethyl-2H-chromene-3-carboxylates under microwave assisted solvent-free conditions. This method has the advantages of short reaction time, high yields (73%~88%), easy operation and environmental friendliness. The synthesized compounds were characterized by IR, NMR, HRMS and X-ray studies.

Key words: microwave, 3-(trifluoroacetyl)coumarins, recyclization, solvent-free

Cite this article

Yang Guoyu, Wang Caixi, Fan Sufang, Xie Puhui, Jin Qiu, Xu Cuilian. Microwave Assisted Solvent-Free Synthesis of 3-(Trifluoroacetyl)coumarins[J]. Chin. J. Org. Chem., 2015, 35(5): 1173-1178.

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微波辅助无溶剂合成3-三氟乙酰基香豆素类化合物

Microwave Assisted Solvent-Free Synthesis of 3-(Trifluoroacetyl)coumarins

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