Study on the Grinding-Induced Solvent-Free Preparation of 3-Styryl-1,5-diketones

doi:10.6023/cjoc201507017

Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (1): 113-120.DOI: 10.6023/cjoc201507017 Previous Articles Next Articles

Articles

无溶剂研磨法快速合成3-芳乙烯基-1,5-二酮类化合物的反应研究

王克虎, 殷雪娇, 陶瑞, 黄丹凤, 苏瀛鹏, 胡雨来, 傅颖, 杜正银, 王进贤

西北师范大学化学化工学院兰州 730070

收稿日期:2015-07-17 修回日期:2015-10-13 发布日期:2015-12-10
通讯作者: 王克虎, 胡雨来 E-mail:wangkh@nwnu.edu.cn
基金资助:
国家自然科学基金(No. 21262031)资助项目.

Study on the Grinding-Induced Solvent-Free Preparation of 3-Styryl-1,5-diketones

Wang Kehu, Yin Xuejiao, Tao Rui, Huang Danfeng, Su Yingpeng, Hu Yulai, Fu Ying, Du Zhengyin, Wang Jinxian

College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070

Received:2015-07-17 Revised:2015-10-13 Published:2015-12-10
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21262031).

1. Study on the Grinding-Induced Solvent-Free Preparation of 3-Styryl-1,5-diketones.PDF(2516KB)

Abstract

A convenient procedure for the synthesis of 3-styryl-1,5-dicarbonyl compounds has been developed under solvent-free grinding conditions. α,β-Unsaturated aldehydes react with aromatic ketones to give the corresponding dienone products, then followed by a Michael addition producing 3-styryl-1,5-dicarbonyl compounds in the presence of NaOH at room temperature. The advantages of this procedure are solvent-free, catalyst-free, mild reaction conditions, simple procedure, and short reaction time.

Key words: solvent-free, grinding, aldol-Michael addition, 1,5-diketones

Cite this article

Wang Kehu, Yin Xuejiao, Tao Rui, Huang Danfeng, Su Yingpeng, Hu Yulai, Fu Ying, Du Zhengyin, Wang Jinxian. Study on the Grinding-Induced Solvent-Free Preparation of 3-Styryl-1,5-diketones[J]. Chin. J. Org. Chem., 2016, 36(1): 113-120.

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无溶剂研磨法快速合成3-芳乙烯基-1,5-二酮类化合物的反应研究

Study on the Grinding-Induced Solvent-Free Preparation of 3-Styryl-1,5-diketones

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