Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones

doi:10.6023/cjoc201612001

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1548-1555.DOI: 10.6023/cjoc201612001 Previous Articles Next Articles

Notes

碘促进吡喃并[3，2-c]喹啉-4，5-二酮类衍生物的有效合成

周婷, 王道林, 钱建华, 赵伟

渤海大学化学化工学院辽宁省功能化合物合成与应用重点实验室锦州 121003

收稿日期:2016-12-01 修回日期:2017-01-11 发布日期:2017-02-17
通讯作者: 王道林 E-mail:wangdaolin@sina.com
基金资助:
辽宁省教育厅创新团队（No.2015001）资助项目.

Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones

Zhou Ting, Wang Daolin, Qian Jianhua, Zhao Wei

Key Laboratory of Synthesis & Application of Functional Compound, College of Chemistry andChemical Engineering, Bohai University, Jinzhou 121003

Received:2016-12-01 Revised:2017-01-11 Published:2017-02-17
Contact: 10.6023/cjoc201612001 E-mail:wangdaolin@sina.com
Supported by:
Project supported by the Innovation Team Project of Liaoning Province Education Department (No. 2015001).

1. Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones.PDF(2221KB)

Abstract

An efficient method for the synthesis of pyrano[3,2-c]quinoline-4,5-dione derivatives via iodine promoted intramolecular cyclization of 1-methyl-3-cinnamoyl-4-hydroxyquinolin-2-one, synthesized from aldol condensation of 1-methyl-3-acetyl-4-hydroxyquinolin-2-one with aromatic aldehydes in the presence of pyridine and PEG-400 under ultrasound irradiation, has been described. This method offers the advantages of a green approach, easy work-up, mild conditions and good yields.

Key words: quinoline, heterocycle, ultrasound irradiation, iodine, synthesis

Cite this article

Zhou Ting, Wang Daolin, Qian Jianhua, Zhao Wei. Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones[J]. Chin. J. Org. Chem., 2017, 37(6): 1548-1555.

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碘促进吡喃并[3，2-c]喹啉-4，5-二酮类衍生物的有效合成

Iodine Promoted Synthesis of Pyrano[3,2-c]quinoline-4,5-diones

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