Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (5): 1206-1231.DOI: 10.6023/cjoc201911004 Previous Articles     Next Articles


余青, 陈晓丽, 刘华, 张奇龙   

  1. 贵州医科大学基础医学院 贵阳 550025
  • 收稿日期:2019-11-04 修回日期:2019-12-21 发布日期:2020-01-15
  • 通讯作者: 张奇龙
  • 基金资助:

Recent Progress in Colorimetric and Fluorimetric Probes for the Detection of Hypochlorous Acid

Yu Qing, Chen Xiaoli, Liu Hua, Zhang Qilong   

  1. Guizhou Medical University, School of Basic Medicine, Guiyang 550025
  • Received:2019-11-04 Revised:2019-12-21 Published:2020-01-15
  • Supported by:
    Project supported by the Science and Technology Foundation of Guizhou Province (Nos. [2019]2792, [2018]5779-14).

Hypochlorous acid (HClO) and sodium hypochlorite (NaClO) exist widely in living organisms and environment and is closely related to the health or disease of living organisms. In recent years, in order to reveal the effect and mechanism of HClO on living organisms, many HClO colorimetric and fluorimetric probes have been designed and applied to the detection HClO or ClO- in environment or living organisms due to their sensitivity, rapidity, high selectivity and real-time monitoring. According to the different recognition mechanism of probes for HClO, HCO colorimetric fluorescent probes are divided into five categories. The design, characteristics and practical application of hypochlorite colorimetric fluorescent probes in the past five years are summarized and evaluated.

Key words: hypochlorous acid, colorimetric and fluorimetric probe, recognition mechanism, application