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About the Cover:
Recently, by taking advantage of substrate-directed strategy, we have developed a number of methods that functionalize internal alkenes with excellent regio-, diastereo-, and enantio-selectivities. In this account, we summarize our work on catalytic asymmetric hydroalkynylation of alkenes and analyze the mechanisms that control the reactivity and selectivity on page 1087. As illustrated in the picture, asymmetric hydroalkynylation of alkenes provides a highway through which various chiral molecules can be rapidly delivered.
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ACCOUNT